WebSep 11, 2024 · Mechanistically, Cited1 interacts with Bmpr2 and Smad4 to activate the Cited1–Bmpr2–Smad1/5/8 axis in the cytoplasm and Cited1–Smad4–p300 complexes in … Web说明反义肽核酸探针能特异性结合并沉默CITED1从而明显抑制肿瘤细胞的增殖。同时, 177 Lu标记的无义探针在1~3 d时相较于其他对照组探针细胞增殖率略微有所下降。其可能的 …
CITED1 - DakaPath
WebCited1 deficiency decreases intestinal tumourigenesis in Apc (Min/+) mice and impacts upon a number of oncogenic signaling pathways, including Wnt. This restraint imposed by Cited1 is consistent with a requirement for Cited1 to constrain Wnt activity to a level commensurate with optimal adenoma formation and maintenance, and provides one ... WebCITED1, MSG1, Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1. External IDs. OMIM: 300149 MGI: 108023 HomoloGene: 3057 GeneCards: … pho lake country
在哪里可以找到权威的肿瘤统计数据? - 知乎
Web近年来,肿瘤免疫治疗(Immunology Oncology Therapy)已成为晚期恶性肿瘤治疗的重要手段之一。肿瘤免疫治疗并不直接攻击癌细胞,而是通过激活人体自身免疫系统来抗击肿 … WebMar 29, 2024 · CITED1 confers stemness to Wilms tumor and enhances tumorigenic responses when enriched in the nucleus. Murphy AJ, Pierce J, de Caestecker C, Ayers GD, Zhao A, Krebs JR, Saito-Diaz VK, Lee E, Perantoni AO, de Caestecker MP, Lovvorn HN 3rdMurphy AJ, et al. Oncotarget, 2014 Jan 30. PMID 24481423 WebNov 6, 2024 · Background: It has been reported that CBP/p300-Interacting Transactivator with glutamic acid [E]/aspartic acid [D]-rich C-terminal domain 1 (CITED1) is overexpressed in papillary thyroid cancer (PTC). However, the functional significance and underlying mechanisms of CITED1 in PTC are largely unknown. Methods: The Cancer Genome … how do you build your own business card