Ctcf和ctcfl
WebCTCFL paralog; transcriptional repressor CTCF; Background Information: CTCF is a ubiquitous 11 zinc finger (ZF) protein with highly versatile functions. A transcriptional repressor, CTCF, binds to promoters of vertebrate c-myc gene. It also binds to the PLK and PIM1 promoters. CTCF may prevent the access of transcriptional activators to enhancers. WebChIPAb+ CTCF - ChIP Validated Antibody and Primer Set clone 1.2.1.5.4, from mouse; Synonyms: 11 zinc finger transcriptional repressor, 11-zinc finger protein, CCCTC-binding factor, CCCTC-binding factor (zinc finger protein), CTCFL paralog, transcriptional repressor CTCF; find Sigma-Aldrich-1710044 MSDS, related peer-reviewed papers, technical …
Ctcf和ctcfl
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Web我们为您找到 ctcf 的 1 个相关产品结果。 ... 生命科学基础与转化研究的主要领域,包括细胞生物学、肿瘤、免疫与炎症、表观遗传学和转录调控、代谢与内分泌、衰老、心血管、干细胞和发育、神经科学、蛋白质翻译后修饰等,还提供病理学研究与伴随诊断 ... WebMany CTCF and CTCFL binding sites overlap with some marked with H3K4me3 and thus most likely represent promoters [77, 78]. Together, GC-rich binding sites were preferentially associated with ...
WebJun 22, 2024 · CTCF is a key organizer of the 3D genome. Its specialized paralog, BORIS, heterodimerizes with CTCF but is expressed only in male germ cells and in cancer states. WebStatistical differences between individual binding categories (CTCFL, CTCF/CTCFL co-bound and CTCF or CTCFL stand-alone sites) and the average CTCF site as reference were calculated by Wilcoxon signed rank test (two-sided alternative: ‘binding in analyzed category is greater than that of CTCF binding’). The corresponding code is available ...
WebApr 1, 2024 · CTCF plays a key role in organizing chromatin into TAD structures but it can also function as a transcription factor. CTCFL (CTCF-like), the paralog of CTCF, is … WebU25435 - Human transcriptional repressor (CTCF) mRNA, complete cds. BC130486 - Homo sapiens CCCTC-binding factor (zinc finger protein)-like, mRNA (cDNA clone MGC:163358 IMAGE:40146517), complete cds. DQ294738 - Homo sapiens BORIS-like protein (CTCFL) mRNA, complete cds, alternatively spliced. BC014267 - Homo sapiens CCCTC-binding …
WebOct 8, 2024 · By PCR screening a testis cDNA library for CTCF-like sequences, followed by 5-prime RACE, Loukinov et al. (2002) isolated a cDNA encoding CTCFL, which they …
WebOct 7, 2014 · Thus, the comparison between CTCF and CTCFL domains revealed that only CTCF harbours the powerful chromatin opening domain within the N-terminus plus zinc finger region. Chromatin opening is usually associated with, or is caused by, histone modifications. Since we found the closed array of the F42B8 cells to be devoid of active … czech internet forumWebMay 11, 2024 · CTCFL and CTCF-CTCFL overlapping binding sites are frequently bound by both CLC and LCL (Fig. 4 d, e), but at some locations, fusion protein peaks are reduced in size compared to that of CTCFL (e.g., at Ctcfl, Prss50, Gal3st1 loci) (Fig. 4 d). Sites bound by CTCF only were preferentially bound by LCL as opposed to CLC (Fig. 4 f). czech inflation newsWebCTCF plays a key role in organizing chromatin into TAD structures but it can also function as a transcription factor. CTCFL (CTCF-like), the paralog of CTCF, is normally transiently … binghamton ice rinkWebCTCFL Antibodies. Antibodies that detect CTCFL can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, … binghamton impound lotCCCTC-binding factor (CTCF), an 11-zinc finger factor involved in gene regulation, utilizes different zinc fingers to bind varying DNA target sites. CTCF forms methylation-sensitive insulators that regulate X-chromosome inactivation. Transcriptional repressor CTCFL (this protein) is a paralog of CTCF and appears to be expressed primarily in the cytoplasm of spermatocytes, unlike CTCF which is expressed primarily in the nucleus of somatic cells. CTCF and CTCFL ar… czech institute - eventsWebMar 29, 2024 · CTCFL regulates the PI3K-Akt pathway and it is a target for personalized ovarian cancer therapy. Transcription Factor CTCFL Promotes Cell Proliferation, … czech in the boxWebOct 8, 2024 · By PCR screening a testis cDNA library for CTCF-like sequences, followed by 5-prime RACE, Loukinov et al. (2002) isolated a cDNA encoding CTCFL, which they termed BORIS. The deduced 663-amino acid protein contains 11 central ZFs, like CTCF, but it has unique N and C termini. EMSA analysis showed an interaction with testis DNA. binghamton ice hockey