WebOct 1, 2008 · The aim of our study was to investigate the relationship of polymorphism (cDNA 385 C-->A) of FAAH gene on obesity parameters in patients with diabetes mellitus type 2. A population of 70 patients ... WebThe lack of Faah promotes the development of obesity as Faah-deficient mice fed with regular diet have higher body weight [156]. Faah-deficiency is associated with increased lipid storage and ...
The influence of the fatty acid amide hydrolase 385C>A single ...
WebDec 3, 2009 · The current study characterizes the relationship between FAAH and obesity-related dyslipidemia, in one of the most rigorously-phenotyped obesity study cohorts in the USA. Materials & methods: Members of 261 extended families (pedigrees ranging from 4 to 14 individuals) were genotyped using haplotype tagging SNPs obtained for the FAAH … WebFAAH 2/ mice had elevated hypothalamic, hepatic and small intestinal AEA and OEA levels [5]. Despite comparable caloric intake, these high-fat fed, FAAH2/2 mice showed obesity and elevated ad-lib glucose and insulin levels implying dysregulation of energy storage and/or expenditure [5]. In our present study, the contributions of liver FAAH ... john alff obituary
Fatty Acid Amidase - an overview ScienceDirect Topics
WebJan 10, 2007 · High fat diet, physical inactivity, and multiple genetic variants are likely to contribute to the development of obesity [], which is becoming an increasing global health burden due to the accompanying risk of common diseases such as type 2 diabetes and premature cardiovascular morbidity and mortality [].The enzyme fatty acid amide … WebJul 8, 2024 · The chronic over-activation of the endogenously produced cannabinoids in obesity has been demonstrated in several studies. A common 385C>A single nucleotide polymorphism of the fatty acid amide hydrolase, one the most important inactivating enzymes of endogenous cannabinoids, has been shown to be associated with obese … john alfieri percussion