Hypoxia-inducible factor 1-alpha, also known as HIF-1-alpha, is a subunit of a heterodimeric transcription factor hypoxia-inducible factor 1 (HIF-1) that is encoded by the HIF1A gene. The Nobel Prize in Physiology or Medicine 2024 was awarded for the discovery of HIF. HIF1A is a basic helix-loop-helix PAS domain containing protein, and is consider… WebDescription hypoxia inducible factor 1 subunit alpha Also known as HIF-1-alpha, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78 Species Homo sapiens Entrez ID 3091 MGC ID BC012527 Plasmids containing this gene, or a homologous gene. Showing 1 to 10 of 33 entries Show entries Search table: Previous 1 2 3 4 Next
Addgene: Plasmids related to HIF1A
WebFigure 2. HIF1A protein in macrophages is elevated in hemophagocytic lymphohistiocytosis (HLH) mouse models. (A) Schematic diagram depicting lymphocytic choriomeningitis virus (LCMV)-infected Prf1 − / − HLH mouse model. Perforin-deficient (Prf1 − / −) mice were infected with or without LCMV-WE of 200 plaque-forming units (PFU) via intraperitoneal … Web15 de nov. de 2024 · HIF1A-deficient cancer cells express a proinflammatory signature that is dependent on glycogen In order to explore the mechanism by which increased glycogen accumulation could contribute to HIF1A-independent tumor growth, we analyzed the signaling pathways upregulated in shHIF1A cells. irds uc merced
Endothelial Hypoxia-Inducible Factor-1α Is Required for Vascular ...
Web21 de mar. de 2024 · HIF1A (Hypoxia Inducible Factor 1 Subunit Alpha) is a Protein Coding gene. Diseases associated with HIF1A include Retinal Ischemia and Enchondromatosis, Multiple, Ollier Type . Among its related pathways are Signaling by PTK6 and Regulation of activated PAK-2p34 by proteasome mediated degradation . Web25 de mar. de 2024 · HIF-1α, an essential transcription factor under hypoxic condition, is indispensable for chondrocytes during skeletal development but its expression and roles in articular chondrocytes are yet to be... Web15 de set. de 2024 · Gene locations for HIF1A-AS1 and HIF1A-AS2 in the human were from chr14:61681041-61695823 and chr14:61747039-61749089. HIF-1α had three transcripts, in which transcript 1 and 2 were from chr14:61695401-61748259 and transcript 3 was from chr14:61697622-61748259. The relative locations of HIF-1α, HIF1A-AS1 and HIF1A … irds symptoms