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WebSpironolactone is an oral acne medication that treats stubborn hormonal acneby controlling androgens, like testosterone, to reduce oil production and keep pores clear. It’s often used in conjunction with a topical acne treatment to prevent and target hormonal acne from different angles. WebAug 18, 2024 · Spironolactone is used to treat high blood pressure and heart failure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. It is also used to treat swelling (edema) caused by certain conditions (such as heart failure, liver disease) by removing excess fluid and improving symptoms such as breathing problems.

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