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WebBackground Methadone is an effective opioid analgesic for severe pain. Because of low cost (a month’s supply may be US $5-10) and apparent efficacy in complex pain syndromes, it … WebApr 12, 2024 · We've demonstrated it's feasible to administer a placebo in addition to standard-of-care methadone in a community-based opioid treatment setting without adding a significant burden to clinic... gabapentin tolerance
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